Growing environmental concerns and shifting regulatory frameworks are driving the home care industry toward more sustainable cleaning solutions. This article investigates a water-soluble spider silk protein as a sustainable alternative raw material for laundry applications. Fluorescence imaging confirms that the proteins form uniform coatings on cotton, polyester, and polyamide fibers, highlighting its strong affinity for a range of textile substrates. These promising results provide a foundation for future research to further investigate and unlock potential performance and sustainability benefits in consumer care formulations.