Ò. Expósito, M. Buchholz, V. Vidal, A. Gallego, S. Ruiz, P. Riera, D. Luna, M. Mas, M. Gibert, L. Cano, S. Laplana, T. Ruiz, R. Ferreira, A. Guirado
Human skin is an electrically active tissue that uses ionic flows to regulate communication, repair, and homeostasis. While high-performance rejuvenation has traditionally relied on external devices, there is growing demand for device-free, biologically driven alternatives that harness the skin’s own bioelectrical capacity. Ignilyte™ responds to this need through plant biotechnology derived from the stem cells of Hylocereus undatus (dragon fruit), a species naturally rich in electrolytes that enable survival in arid environments.
Developed from dragon fruit stem cells, this active ingredient features a secretome enriched in Plant electrines™ – a synergistic combination of biomolecules designed to reactivate the skin’s bioelectricity. Acting as a biological electrostimulator, it operates via a two-step mechanism: modulation of P2X receptors to promote extracellular ATP release, followed by electroporation-like activity that transiently increases membrane permeability and enables efficient self-delivery of bioactives. Once internalized, these compounds stimulate key markers of regeneration, including vascular epithelial growth factors (VEGF) and pro-collagen I.
Clinical studies demonstrate significant improvements in global facial rejuvenation, wrinkle depth, eyelid sagging, and eyebag volume, supporting Ignilyte™ as a non-invasive, device-free solution for global facial rejuvenation and a new bioelectric-mimetic paradigm in dermocosmetics.
