For decades, skincare has led the beauty industry’s most meaningful scientific breakthroughs. Today, haircare is poised to follow. At the center of this shift is biotechnology, specifically, growth factors that work with the body’s natural regenerative pathways. Core Biogenesis is advancing this evolution with a novel, plant produced Oleosome Growth Factor Fusion that brings clinically validated skincare science directly to the scalp.
Growth factors are among the most powerful bioactives used in modern skincare. As human-identical (biomimetic) proteins, they play a key role in cellular communication, supporting skin renewal, barrier repair, and visible improvements in aging. Yet despite their proven biological potential, growth factors have historically faced one major challenge: delivery. Proteins are inherently fragile, prone to degradation, and difficult to stabilize within cosmetic formulations, especially when they must interact with the skin’s outermost barrier.
Core Biogenesis addresses this challenge through its proprietary oleosome fusion technology. Oleosomes are naturally occurring lipid structures found in plants, designed by nature to protect and transport sensitive biomolecules. By fusing biomimetic growth factors such as epidermal growth factor (EGF) and fibroblast growth factor 2 (FGF-2) to these oleosomes, Core Biogenesis creates a delivery enabled active that improves protein stability and enhances bioavailability at the skin surface.
This technology has already demonstrated strong clinical performance in skincare. Independent studies show visible improvements in wrinkles, firmness, pigmentation, and barrier function within just 14 days, with results benchmarked against retinol. These findings position oleosome growth factor fusions as a compelling alternative for brands seeking high efficacy without compromising skin tolerance.
The next question was inevitable and transformative: if this delivery system can unlock growth factor performance in skin, could it do the same for the scalp?
For the first time, Core Biogenesis is presenting independent clinical data evaluating an Oleosome FGF-2 fusion specifically designed for haircare applications. The scalp, like facial skin, is a biologically active environment where cellular signaling plays a critical role in hair quality and growth behavior. By targeting scalp biology rather than the hair fiber alone, this new active reframes haircare as an extension of skin science.
Clinical results reveal measurable improvements across key scalp and hair parameters, including hair density, hair shaft thickness, and indicators associated with the hair growth cycle. These findings suggest that when growth factors are delivered effectively, they may support a healthier scalp environment, laying the foundation for fuller, stronger looking hair over time.
Beyond performance, the technology reflects a broader shift in beauty innovation. The Oleosome FGF-2 fusion is plant-produced, non-animal, and designed to integrate seamlessly into modern formulations. It offers brands a clean, sustainable pathway to advanced biotechnology without sacrificing transparency or formulation flexibility.
By bridging established skincare biotechnology with emerging haircare science, Core Biogenesis is helping redefine what performance haircare can be. Delivery enabled protein actives like oleosome growth factor fusions challenge traditional category boundaries and point toward a future where scalp health, skin biology, and hair performance are addressed through one unified, science driven approach.
As dermaceuticals and performance haircare continue to evolve, the message is clear: the next generation of results won’t come from ingredients alone, but from how intelligently they are delivered.
Watch the video of Alex Reeber, CEO of Core Biogenesis, titled “Core Biogenesis Story - From Unexpected Discovery to the Future of Anti-Aging”
Tony Abboud, CCo, Core Biogenesis
tony.abboud@corebiogenesis.com
