Beyond Collagen: How NeoColla™ is Advancing Skin Longevity
Interview with Divyesh Patel,
Regulatory & Sustainability Manager at TRI-K Industries
What exactly are the exosomes in NeoColla™?
NeoColla™ utilizes plant-derived extracellular vesicles (EVs) sourced from Centella asiatica cell culture. These vesicles act as biological messengers containing naturally occurring lipids, proteins, peptides, and signaling molecules that support skin communication pathways.
How are plant exosomes different from human or animal-derived exosomes?
Plant-derived exosomes offer a more sustainable, scalable, and consumer-friendly approach while avoiding ethical, regulatory, and safety concerns associated with animal or human-derived materials. They are particularly attractive for cosmetic applications due to their compatibility with natural and biotechnology positioning.
How do the exosomes and Ganoderma peptides work together?
The exosomes support cellular communication and regenerative pathways, while the hydrolyzed Ganoderma peptides provide biomimetic structural support by helping reinforce the extracellular matrix and improving skin resilience. Together they address both skin function and structure.
How does NeoColla™ compare to traditional collagen ingredients?
Unlike topical collagen, which primarily acts as a moisturizer and film former, NeoColla™ combines biological signaling with structural support, addressing multiple pathways associated with skin aging.
Based on the close results of the synthetic peptide benchmark compared to NeoColla™, what are the advantages for the customer to purchase products with NeoColla™?
NeoColla™ delivers comparable clinical efficacy while offering a differentiated and unique dual-action mechanism in a next generation naturally derived ingredient that combines plant-derived extracellular vesicles with Ganoderma peptides. We found that specifically Centella asiatica exosomes have the ability to stimulate procollagen 1 and have strong anti-inflammatory activity. We also found Ganoderma peptides demonstrated very strong upregulation of the gene (P4HA1) that stimulates the conversion of procollagen into mature collagen fibers and high anti-oxidant activity. The synergy between the two aligns with key market trends in regenerative beauty, skin longevity, and biotechnology, giving brands a stronger innovation and marketing story.
Can you show that the production process and materials are environmentally friendly?
NeoColla™ uses plant cell culture technology of Centella asiatica and enzymatic hydrolyzation of Reishi mushroom, which reduces reliance on traditional agriculture by minimizing land use, water consumption, and pressure on natural resources. This biotechnology approach also provides consistent quality and supports our broader sustainability goals.
Which events will you attend this year where customers can learn more about NeoColla™?
We will have representation at SEPAWA, SCS Formulate, in-cosmetics Latin America, in-cosmetics Asia, and more, where we'll be happy to discuss the science, clinical data, and formulations, with samples available and we welcome attendees to stop by and learn more. You can find all of our upcoming events at https://www.tri-k.com/events.
